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Amyloidosis

Amyloidosis

About Amyloidosis

Amyloidosis is when an abnormal protein called amyloid builds up in your tissues and organs. 
As the amount of amyloid protein deposits increase in a tissue or organ, they interfere with the tissue or organ’s healthy function. Eventually, the amyloid protein deposits cause symptoms and organ failure. Amyloidosis is a serious health problem that can lead to life-threatening organ failure.

Amyloid protein deposits, or amyloidosis, may be localized to organs, such as the lung, skin, bladder, or bowel, or they can be systemic. “Systemic” means that the deposits may be found throughout the body. Systemic Amyloidosis is the most common. Although Amyloidosis is not a type of cancer, it may be associated with certain blood cancers like Multiple Myeloma.

Amyloidosis is a very rare disorder. Because it is such a rare disorder, it has been difficult to study. However, doctors, homeopaths, and researchers, have begun to understand more about Amyloidosis over the past few decades. Research continues to uncover more about this disorder.

Types of Amyloidosis

There are different types of Amyloidosis, including the following:

• AL Amyloidosis (Immunoglobulin Light Chain Amyloidosis). This is the most common type and used to be called Primary Amyloidosis. AL stands for “Amyloid Light chains,” which is the type of protein responsible for the condition. There’s no known cause, but AL Amyloidosis is a disorder of the plasma cells. Plasma cells are a type of white blood cell responsible for the production of immunoglobulins or antibodies, which are a type of protein that fights infection. In AL Amyloidosis, the light chain proteins are misshapen and produced in excess. They deposit in tissues and can damage one or more organs. The heart, kidneys, nerves, and gastrointestinal system are the most common organs affected. Because AL Amyloidosis is associated with the overproduction of plasma cell proteins, it is linked to Multiple myeloma.

• Autoimmune (AA) Amyloidosis. AA Amyloidosis is also called “Secondary Amyloidosis” or “Inflammatory Amyloidosis.” In this condition, the amyloid protein that builds up in the tissues is called the A protein. AA Amyloidosis is associated with some chronic diseases, such as diabetes, tuberculosis, rheumatoid arthritis, Crohn’s disease, or ulcerative colitis and inflammatory bowel disease. It may also be linked to aging. AA Amyloidosis can affect the spleen, liver, kidneys, adrenal glands, and lymph nodes. Lymph nodes are tiny, bean-shaped organs that fight infection.

• Hereditary or Familial Amyloidosis. Hereditary myloidosis is rare. It can be passed from generation to generation within a family. The proteins produced in Hereditary Amyloidosis may cause problems with the heart and may cause carpal tunnel syndrome and eye abnormalities. The most common subtypes involve a protein called transthyretin (TTR).

,• Dialysis-Related Amyloidosis (DRA). This is more common in older adults and people who have been on dialysis for more than 5 years. This form of amyloidosis is caused by deposits of beta-2 microglobulin that build up in the blood. Deposits can build up in many different tissues, but it most commonly affects bones, joints, and tendons

Symptoms of Amyloidosis

Symptoms of Amyloidosis are often subtle.
The symptoms of amyloidosis can vary widely, depending on the specific organ or number of organs affected by the buildup of amyloid protein(s). Or the cause of a symptom may be another medical condition. All of these factors can make diagnosing amyloidosis challenging because the symptoms may be similar to those of numerous other diseases and conditions that are more common than Amyloidosis.

Symptoms of Amyloidosis are usually determined by the organ or function that is affected by the protein buildup. For example:

• Kidneys – Amyloidosis in the kidneys will reduce the kidneys’ ability to filter waste and break down proteins. As a result, large amounts of protein may be found in the urine, causing “foamy” urine. The kidneys may even stop working. Decreased urine output and high creatinine may be present.

• Liver – Amyloidosis may cause the liver to grow larger and affect its ability to function normally. This may cause pain in the upper abdomen, swelling in the abdomen, and changes in liver enzymes that can be found using blood tests.

• Heart – Amyloidosis of the heart may cause an irregular heartbeat, called an arrhythmia; enlarge the heart; and cause poor heart function, resulting in fluid buildup, an irregular heartbeat, shortness of breath, or chest pain.

• Gastrointestinal tract – Amyloidosis of the gastrointestinal tract may cause problems with the digestion and absorption of food nutrients, diarrhea or constipation, bleeding, blockages, and a thickened tongue, called macroglossia. It may also cause problems with the esophagus, including gastroesophageal reflux disease (GERD).

• Thyroid gland – Amyloidosis of the thyroid gland may cause goiter, a noncancerous swelling of the thyroid gland.

• Lungs – Amyloidosis of the lungs may cause problems with breathing, including shortness of breath.

• Nervous system – Disorders of peripheral nerves are the most common neurological complications of Amyloidosis. Patients may experience painful paresthesias (unusual sensations), numbness and balance difficulties, vomiting, diarrhea, constipation, sweating, or sexual problems. Numbness, tingling, or weakness in the arms or legs may develop. This condition is known as peripheral neuropathy. Carpal tunnel syndrome may also occur.

Other general symptoms of Amyloidosis include:

• Fatigue, which is extreme exhaustion or tiredness. It is a common problem for people with Amyloidosis. Patients who feel fatigue often say that even a small effort, such as walking across a room, can seem like too much. 

• Unexplained weight loss.

• Anemia, which is a low level of red blood cells.

• Weak hand grip, which may arise from carpal tunnel syndrome.

• Skin changes, such as a rash around the eyes.

• Clay-colored stools.

• Joint pain.

• Risk of infection; people with AL amyloidosis are at increased risk of getting an infection. This is because this type of Amyloidosis causes abnormalities in plasma cells. Plasma cells produce immunoglobulins, which help fight infection. A condition called leukopenia occurs when the body does not have enough white blood cells and is less able to fight off infections. Some white blood cells, called neutrophils, can destroy harmful bacteria and fungi. People with leukopenia or neutropenia, a low level of neutrophils, are more likely to develop a serious infection.

Risk Factors for Amyloidosis

The following factors may raise a person’s risk of developing Amyloidosis:

• Age – The risk of Amyloidosis increases as a person gets older. For AL Amyloidosis, the majority of people diagnosed are older than 40.

• Gender – Amyloidosis is more common in men than in women.

• Other diseases – As explained above, Amyloidosis is sometimes linked with another disease. For instance, research shows that 12% to 15% of people with multiple myeloma also develop AL Amyloidosis.

• Family history – Hereditary Amyloidosis can run in families. This may be due to a genetic change, called a mutation, that is passed down from generation to generation.

• Amyloidosis may also happen in people with end-stage kidney disease who are on dialysis for a long time.

Diagnosing Amyloidosis

Only your doctor can make a diagnosis of Amyloidosis because symptoms of Amyloidosis are often subtle and similar to those other numerous diseases.
A thorough physical examination and a detailed and accurate account of your medical history are crucial in helping your doctor diagnose Amyloidosis.

Blood and urine tests can spot abnormal proteins. Depending on your symptoms, your doctor may also check your thyroid and liver.

Your doctor will do a biopsy to confirm a diagnosis of Amyloidosis and know the specific type of protein you have. A biopsy is the only sure way for the doctor to diagnose Amyloidosis.
Imaging tests may be used to find out whether organs, such as the heart or kidneys, are affected.

Homeopathic Treatment of Amyloidosis

Homeopathic medicines are well capable to treat the underlying causes of Amyloidosis along with treatment for another medical condition. Most importantly, we are happy to say despite its challenging diagnosis, Amyloidosis is quite easily and conveniently treatable under our protocol at Farm Herbal Pro.

For your homeopathic medicines and treatment for Amyloidosis, contact the homeopath Oluwafunmise on 08028366901 or 08183554665

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Olufunmise Odubore